Mozzarella Pesto Chicken Grilled Cheese

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This satisfying sandwich transforms simple ingredients into something special. Start with sturdy sourdough bread, slather one side with aromatic basil pesto, then pile on tender shredded chicken and fresh mozzarella slices. The magic happens in the skillet—butter the exterior and press until each side achieves deep golden crunch while the cheese melts into gooey perfection. The pesto infuses every bite with herbaceous brightness, perfectly balancing the rich, melted mozzarella and savory chicken. Ready in just 20 minutes, this creates a meal that feels both comforting and slightly elevated, ideal for lunch or a quick dinner.

Updated on Wed, 21 Jan 2026 15:14:00 GMT
Golden-brown Mozzarella Pesto Chicken Grilled Cheese on sourdough, showing melted cheese and fresh basil garnish. Save
Golden-brown Mozzarella Pesto Chicken Grilled Cheese on sourdough, showing melted cheese and fresh basil garnish. | goldentalaxt.com

The smell of melting mozzarella always pulls me into the kitchen, but there was something magical about the first time I combined pesto with leftover chicken. I was standing at the stove on a rainy Tuesday, just trying to use up a rotisserie chicken from the night before. The moment I took that first bite, I knew this wasnt just leftovers anymore.

I made these for my sister last month when she was having a rough week at work. She took one bite and actually stopped talking for a full minute, which never happens. Now she texts me randomly asking when Im making them again.

Ingredients

  • Sourdough or Italian bread: The sturdier texture holds up beautifully to all those fillings without getting soggy
  • Fresh mozzarella: Slice it yourself if you can because it melts into those amazing cheese pulls everyone loves
  • Cooked shredded chicken: Rotisserie chicken works perfectly here, especially when youre short on time
  • Basil pesto: Homemade is wonderful but dont stress about it, a good store bought version works just fine
  • Unsalted butter: Softening it ahead of time makes spreading so much easier and more even

Instructions

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Build your base:
Lay out all four bread slices and spread that generous layer of pesto on two pieces, right to the edges
Layer the good stuff:
Pile your shredded chicken over the pesto, then arrange the mozzarella on top so every bite gets cheese
Add the extras:
Tomato slices and fresh basil make it special, while Parmesan adds this salty kick that cuts through the richness
Close it up:
Top with the remaining bread slices, then butter the outside of both sides thoroughly
Get that golden crunch:
Cook in a hot skillet for about four minutes per side, pressing gently with your spatula
The waiting game:
Let them rest for just one minute before cutting, otherwise the cheese will ooze right out
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Boil water quickly for tea, coffee, instant soups, and faster prep when cooking grains or noodles.
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A close-up of a Mozzarella Pesto Chicken Grilled Cheese, cut diagonally to reveal juicy shredded chicken and pesto. Save
A close-up of a Mozzarella Pesto Chicken Grilled Cheese, cut diagonally to reveal juicy shredded chicken and pesto. | goldentalaxt.com

My neighbor caught the smell through an open window once and knocked on my door to investigate. We ended up eating grilled cheese on the back porch while the sun went down, talking about nothing and everything.

Bread Choices That Work

Sourdough is my go to because the tanginess balances the rich pesto and cheese perfectly. Ciabatta creates this incredible airy crunch, while multigrain adds a nutty element that really works with the basil. Whatever you choose, make sure its fresh enough to hold together but sturdy enough to handle all those fillings.

Make It Yours

Sometimes I add a thin layer of sun dried tomatoes for extra depth, or swap in provolone for a sharper cheese flavor. My husband likes a dash of red pepper flakes for heat, while my friend from college swears by adding a few arugula leaves for freshness. The beauty of this recipe is how well it adapts to whatever youre craving.

Perfect Pairings

A crisp white wine cuts through the richness beautifully, but an icy sparkling water with lemon works just as well. I like serving it with a simple side salad dressed with balsamic vinaigrette to balance all that cheese. On cold nights, a cup of tomato soup alongside makes it feel like childhood comfort food but elevated.

  • Cook everything in the same pan to minimize cleanup
  • Wrap any extras in foil and reheat in the oven for lunch tomorrow
  • Double the recipe because these disappear faster than you expect
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This hearty Mozzarella Pesto Chicken Grilled Cheese features toasted bread and gooey mozzarella, perfect for a quick lunch. Save
This hearty Mozzarella Pesto Chicken Grilled Cheese features toasted bread and gooey mozzarella, perfect for a quick lunch. | goldentalaxt.com

Theres something about a hot pressed sandwich that makes even an ordinary Tuesday feel special. Hope this recipe finds its way into your regular rotation.

Recipe FAQs

What type of bread works best?

Sourdough or Italian bread provides ideal structure and flavor. The sturdy texture holds up well to pressing and toasting without becoming soggy from the pesto and melted cheese. Ciabatta or multigrain also work beautifully for different textures and flavor profiles.

Can I use leftover chicken?

Absolutely. Rotisserie chicken, grilled breasts, or poached chicken all work perfectly. Simply shred or chop into bite-sized pieces. Using pre-cooked chicken makes this an excellent way to transform leftovers into an entirely new meal.

How do I get the crispest exterior?

Use softened butter spread evenly on the outside of each slice. Cook over medium heat, allowing 3–4 minutes per side. Don't rush—the slower cooking ensures the bread achieves deep golden color and maximum crunch while the cheese fully melts.

Can I make this vegetarian?

Yes. Replace the chicken with grilled vegetables like zucchini, roasted peppers, or eggplant. You could also add layers of fresh tomatoes and spinach. The pesto and mozzarella provide plenty of savory richness without meat.

What pairs well with this sandwich?

A crisp Italian white wine like Pinot Grigio cuts through the richness. For non-alcoholic options, try sparkling water with lemon or a light arugula salad dressed with balsamic vinaigrette. Simple sides let the sandwich remain the star.

Can I assemble ahead of time?

It's best to assemble just before cooking to prevent the bread from becoming soggy. However, you can prep all components in advance—shred the chicken, slice the cheese, and have the pesto ready—then assemble and cook quickly when ready to eat.

Mozzarella Pesto Chicken Grilled Cheese

Crispy sourdough loaded with tender chicken, vibrant pesto, and gooey mozzarella, pressed to golden perfection.

Prep time
10 minutes
Cook duration
10 minutes
Overall time
20 minutes
Written by Trevor DeLaCruz


Skill level Easy

Cuisine type American/Italian Fusion

Total yield 2 Portions

Dietary info None specified

What you'll need

Bread & Dairy

01 4 slices sourdough or Italian bread
02 4 oz fresh mozzarella, sliced or shredded
03 2 tbsp unsalted butter, softened

Protein

01 1 cup cooked, shredded chicken breast

Sauces & Spreads

01 3 tbsp basil pesto

Optional Add-Ins

01 2 tbsp grated Parmesan cheese
02 1 small tomato, thinly sliced
03 Fresh basil leaves

How to make it

Step 01

Assemble Bread Base: Lay out all four bread slices. Spread 1 to 1.5 tablespoons basil pesto evenly onto two of the slices, ensuring complete coverage to the edges.

Step 02

Layer Protein: Distribute the shredded cooked chicken breast evenly over the pesto-covered bread slices, pressing gently to adhere.

Step 03

Add Cheese and Toppings: Layer fresh mozzarella over the chicken. Add tomato slices and fresh basil leaves if desired. Sprinkle grated Parmesan cheese across the top for additional flavor depth.

Step 04

Close Sandwiches: Place the remaining plain bread slices on top to complete the sandwiches, pressing down firmly to secure the layers.

Step 05

Butter Exteriors: Spread softened butter generously on the outside of both top and bottom bread slices, ensuring full coverage for even golden browning.

Step 06

Grill Sandwiches: Heat a large skillet or grill pan over medium heat. Place buttered sandwiches in the pan, pressing down slightly with a spatula. Cook for 3 to 4 minutes per side until bread achieves deep golden brown color and cheese melts completely.

Step 07

Rest and Serve: Remove sandwiches from skillet and let rest for 1 minute to allow cheese to set. Cut each sandwich in half diagonally and serve immediately while hot.

Gear needed

  • Large skillet or grill pan
  • Spatula
  • Sharp knife
  • Cutting board

Allergy details

Look over each item for allergens. If not sure, always talk to your healthcare provider.
  • Contains dairy (mozzarella, butter, Parmesan), wheat/gluten (bread), and tree nuts (pesto with pine nuts). Verify store-bought pesto for additional nut and cheese allergens.

Nutrition info (one serving)

For your general understanding only. Medical advice should always come from health professionals.
  • Energy: 520
  • Fat content: 27 g
  • Carbohydrates: 32 g
  • Proteins: 36 g